ASME STP-PT-065 PDF

ASME STP-PT-065 – Branch Leg Study for Bioprocessing Equipment

The purpose of this document is to provide information on the flow conditions required to displace airfrom piping branches in a timely manner. When air is displaced from the branched fitting, the cleaningsolution comes in contact with the branched piping components being cleaned-in-place (CIPed) andeffective cleaning can occur. Without contact of CIP solutions, there is no cleaning. Note: The actualcleaning of process piping is more complicated than simply supplying an adequate flow rate (it involvesmany other factors such as the reagent concentration, temperature, contact time, etc.) and cleaningprocesses are outside of the scope of this document. The focus of this document is on the flow conditionsrequired to ensure contact of the cleaning solution with the branched fittings – a key requirement forcleaning.